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Insulin Glargine
Question: what is the consequences of mixing insulin aspart and insulin glargine?
Answer: mixing different insulins can affect the peak performance time of both and could result in a severe hypo episode.
Question: what should I do ?I mistakenly injected 30 unit of novorapid insulin instead of glargine? it is urgent .no doctor avaiable.
Iget normally 5 unit of novorapid before meal and 30 unit of glargine for 24 hours.
Answer: i think you are not in trouble because you are still alive you still manage to ask yahoo answers .but wait until you collapsed because of severe hypoglycemia. next time careful ,and do not forget to consult your endocrinologist.
Question: which insulin is better and why? Glargine (lantus) or Levimer? i've changed insulin from Glargine lantus to levimer
was this a wise choice and what do you think of these?
Answer: Hi,
i think it depends on your lifestyle.
I was on levemir and it wasn't that good for me, it would wear out towards mid-afternoon for me.
However lantus (which im currently on) will lower my bloods sugars early hours in the morning
Question: What is Glargine (insulin)?What is the starting dose? Is oral medication is still required? If yes what medicine?
Answer: Glargine Insulin is also called LANTUS.
This is a slow-acting, basal insulin. It is injected once or twice a day.
The dosage depends on your current state of health and your weight. Your doctor will advise you.
Oral medication may or may not be used with Lantus. None are REQUIRED. Again, your doctor will advise you.
Most Lantus patients ALSO take a BOLUS insulin injection (like Humulin R) just before each meal. AGAIN, your doctor will advise you.
When taking ANY kind of insulin, always stay in close and frequent contact with your doctor!
Question: what is Glargine insulin? What wii be the starting dose?
Answer: It's a super-long-acting insulin, under the brand name Lantus. If you have been on a previous long-acting insulin such as Ultralente or NPH, your doc will use a formula to determine how much Lantus to start you with, then based on your BG results they can make adjustments from there. Just be forwarned...they market it as a "24-hour" insulin, but for many people it only lasts 18 hours or so. So they might have you take it twice a day instead of just once a day. Also, it cannot be mixed with other insulins, so you'll have to use a separate syringe and give it to yourself in a separate shot from your fast-acting.
Insulin pumps work best, so if the Lantus isn't working great, ask your doc or diabetes educator about getting on a pump.
Question: what are the prices for one vial glargine(lantus) insulin and nuvolog? please answer me the prices according to your country
Answer: Novolin ge Toronto or 50/50 mix pen refills, pack of 5
$119.85 Canadian
Question: How much does insulin Glargine (Lantus) cost in Germany?? Its by the company Aventis and is available in Germany.I wanted to know the cost of both the vial and the optiset .Am aware its available in India but would like to know how much it costs in Germany........
Answer: i am from germany, the insurance pays for it, also the pen, had it for years, but i dont know the price, dont u have insurance?
Im in the US, i still use lantus here, insurance pays for it also, but it still comes from germany, i think its about 300 euro for 6 vials
Question: Does anyone who takes the medication, Lantus Insulin Glargine, feel itchy after they inject it? My 9 yr old says she's itchy after every injection. Luckily it's just once a day, but she doesn't like it. We've asked her diabetes clinic & the pharmacy & they said that no one else has complained. The pharmacy suggested that she takes benadryl a half hour before she needs her shot. But then she's so sleepy afterwards. I don't like to drug my kids if I don't have to. So I guess that my question is:does anyone else feel any side effects to the medication?
She feels itchy all over & there are no bumps or red patches. Just her claw marks where she has scratched. I know what allergic reactions look like & she doesn't have any sign of 1. The itchiness can last for hours.
Answer: It's not surprising. Especially for a kid. Adults complain about "pain" at the injection site. Kids might call it itchy.
First of all it's cold. Warming it up might help some. The other reason might be the chemical nature of the insulin itself.
Lantus is a clear solution as the pH it is suppled in. When it is injected, the acidity changes. The insulin is no longer soluble and crystallizes out. This is what makes it release so nicely over 24 hours. It is also what I suspect is causing the itch. Benadryl won't help. You're probably just stuck.
You sound like a good parent. Keep it up, and keep asking questions
Question: what is glargine insulin? for diabetes
Answer: It is a long acting insulin which you can inject once a day. This has lesser hypoglycemic side effects.
Question: Glargine insulin? who know how dose it work?
Answer: Here are a couple of websites to help you. It also depends on the dosage your doctor has prescribed to you.
http://www.medicinenet.com/insulin_glargine-injectable/article.htm
http://www.marvistavet.com/html/body_glargine_insulin.html
Good luck!
Question: What's the deal with glargine insulin being linked to cancer? i'm diabetic and i take glargine as a night time, long lasting insulin, but my doctor recently told me that it has links to cancer. anybody know anything about it? i'm a little worried.
Answer: No big deal.
The links between Lantus and cancer were statistically insignificant. In fact, the study was inconclusive on the cause of the cancer -- was it REALLY Lantus, or was it caused by the patients being old and/or overweight? [BOTH of these are statistically more important cancer indicators.]
The study urged that much more research was needed, and that patients should NOT stop using Lantus out of fear.
the fact is, the good that Lantus does (keeping you healthy) is MUCH more important than a very small, statistically insignificant chance of getting cancer.
The link below is to the original article in the Wall Street Journal.
Question: I want to shift to glragine and nuvolog insulin do i use insuln between meals when i have a snack ? I am a case of IDDM WITH TWICE DAILY MIXTARD 30/70 INSULIN INJECTIONS.I WANT TO SHIFT TO GLARGINE AND NUVOLOG INSULIN .BEFORE MEALS I SHOULD INJECT NUVOLOG BUT DO I INJECT IT FOR SNACKS BETWEEN MEALS .IF I DONT DO .DOES MY BLOOD SUGAR GO HIGH?
Answer: When I took lantus and novolog I injected the novolog with a carb ratio everytime I ate more than 15 grams of carb. So if I had a 5 gram snack, I didn't inject, but if I have a 30 gram snack, I did. This allowed me to have a treat like ice cream between meals if I wanted to.
I occasionally went high, and then I injected extra when I was above 130 more than 2 hours after a meal.
Question: Two Insulin questions!? What should you do if you accidentally take double the dose of your Lantus (Insulin Glargine/24-hour) insulin?
What happens if a non-diabetic injects insulin into their body?
how many grams of carbs would they have to eat?
Answer: Did you do this or are you talking about theory?
You can call the pharmacy, and discuss it with them, and they will give the best advice without having to talk to your doctor's office.
They might just say to eat something, so the extra insulin will turn that extra blood sugars into body fat, and nothing more to worry about. Or they might advise waking up at 2 am, and eat a gram cracker and some apple juice if your sugar level is to low.
Good Luck!
Question: How many mg/dl of blood suger can be corected by one unit Humalog insulin according to your experiece? I am a case of IDDM get use of Glargine as basal and Humalog for covering the meals and extra blood sugaer .I want to know for example if before meal my blood sugar is 200 mg.dl how many Humalog is needed to correct my BSto 80mg/dl.I know for the meal I should take insulin according to the quantity of carbs I use.Thanks a lot
Answer: This is called a correction factor or senstitivity factor. There's a formula that you can use to figure this out. This works best for someone who has type 1, but those who are using both long acting insulin and fast acting like humalog can use it too. Everyone is different so there's not one number that works for everyone. This formula also works best for those who know that their long acting insulin is set correctly, not causing lows with too much and not causing highs from too little. First figure out how many TOTAL units of insulin you're using, both your long and fast acting insulins. Then look at how much of the total your long acting insulin makes of up of this number. Most people will use 50% of their total insulin as long acting, and the other half will be 50% fast acting, on average. If this is you, divide 1800 by your TOTAL units of insulin per day. For example, if you use 40 units total per day divide 1800 by 40 which would give you 45. One unit of insulin will lower you 45 points. If your long acting insulin makes up LESS than 50% of your TOTAL insulin per day, (but it shouldn't be less than 40%, that would mean you need to make adjustments to your insulin) you can use 1600 to 1800 to divide into. If your long acting insulin is MORE than 50% (but not higher than 60%, again, this means your insulin needs to be adjusted) you can use anything between 1800 and 2200 to divide into. You should speak to your doctor before attempting these formulas and when figuring them you should test a lot to make sure your glucose doesn't drop to low until you are sure you have the correct dose figured out. This is called the 1800 rule. You can learn more about it in a book called Using Insulin. Or for pumpers you can find it in Pumping Insulin.
Question: What is the diference between the hipoglycemia caused By glargine (Lantus) and other insulinch as REGULA? IT IS sid that the hipoglycemia caused by lantus insulin may be different by hipoglycemia caused by another insulin. it may take longer to get better ? what should be done if hipoglicemia happened by Lantus insulin and how should i recogognize that hipo is caused by Lantus?
Answer: Lantus is a long acting insulin, therefore the only difference between the hypoglycemia caused by Lantus and the hypoglycemia caused by regular insulin is that the hypoglycemia caused by Lantus might be a little more tenacious in that the blood sugar will tend to dip again. Otherwise they are indistinguishable and have the same symptoms.
Question: Taking Lantus 2x/day, sugar is testing normal after eating, should I still administer? My cat has diabetes and regulating her has been damn near impossible. Her sugar was almost alway above 400 for months, even on her prescription food. I switched her off the $25/small bag food to canned food with no wheat gluetin and her BS has been much lower.
Normally she gets two 4 unit shots of Lantus (insulin glargine) a day, 12 hours apart. However now that she has finally been testing in the normal range I am scared to give her the 4 units now and have her go into hypoglycemic shock while I'm asleep.
Just to give you the full pic:
Cat normal bs range = 120-180
She is right now at 128. She ate around 10pm. A few days ago she was over 200 when I gave her her post meal shot and when I tested her bs before she ate in the am it was 48!
Lantus is a longer acting insulin. I am thinking she may be ready to go to one shot a day.
Any advise would be greatly appreciated. I am not putting this under pets because I'm sure there are more people here with info on human diabetes. Cat diabetes is the same thing, just a tad bit of a higher "normal" range. Lantus is prescribed to people with diabetes and I use a regular blood sugar monitor to check her bs.
I guess what I'm trying to ask is what would be recommended for a person under these circumstances.
Answer: If she's testing normal, then the Lantus is doing its job.
As it happens, I take Lantus myself, and I only take it once a day. I take a whopping big dose (200 units, yes, that's right, two hundred) but then I am much larger than any house cat. I do sometimes have to take Humalog when I've made unwise food choices.
You should really ask your vet about this. There are people who know a lot about diabetes in this section, but there are also some total nutjobs who hang out around here, too.
Question: Question for Diabetics? I am a diabetic taking Novorapid 3 times a day and Lantus (Insulin glargine) at night. When I inject the Novorapid I prime the needle first and when I inject not only do I not feel the needle go in but I don't feel the insulin go in either. With the Lantus I prime the needle as normal and inject and it doesn't matter where I inject it stings like hell - I alternate my injection sites, but it's always the Lantus that hurts. Does anyone else have the same problem? My blood sugars are very well controlled on both sorts of insulin before you ask. I'm just interested in other people's experiences.
The Lantus and Novorapid which I use currently are kept in my "diabetes" bag at room temperature. The new ones I am not using are stored in the fridge. So it's definately not temperature - wondered whether it may be thicker than the novorapid???
Thanks to all those who have answered my question. It certainly makes sense that the lantus is soluble and is crystal based. I'm glad I'm not the only one who finds injecting Lantus painful. I've tried all sorts to stop it from stinging. It actually starts stinging as soon as the needle is inserted in my skin. Usually it has a couple of droplets of lantus on it from where I've primed the needle. Thank you fellow diabetics and nurses for your help.
Answer: If your Lantus is cold, it will sting really bad. Try warming it up between your hands for a few minutes before injecting, that should help.
Question: Accidental injection of insulin into vein? I think my partner accidentally hit a vein while injecting 34 IU glargine just now. How long is she in danger of overdose before we know for sure she didn't inject directly into a vein???
Not only was the first person to answer rude as all get out, she was also dead wrong! I know what can happen... her blood sugar can bottom out and she can go into insulin shock. My QUESTION was how long before she is out of the woods for such a thing to happen? And BTW rude person... I'm a nurse you azz hat!
THANK YOU VAMP!!!!! I wasn't sure of the time frame. So far in the last 15 minutes her BS has gone UP 13 points. But she is now sick to her stomach, but no headache. I am taking her BS every 10 minutes till it levels off. THANK YOU AGAIN!!!!!
Oh, and it was a total accident. When she withdrew the needle from her abdomen blood welled up from the site. Which of course means she could have accidentally hit a sub-q capillary.
Okay... now it's down 30 points! YIKES! I gave her some candy, and I'll keep checking her sugar levels for awhile. 34 units is a LOT of insulin!
Answer: Hi Robin,
Insulin used to have to be injected into the vein a few years ago, it will do her no harm but to cover a hypo possibility (obviously when injected into the vein it wouldn't;t have been as much as 34u) give her some lucozade or a biscuit. OK so her BS level will go up for a while but better that than a hypo.
Keep her as still as possible so that she doesn't ;t use up any sugar for roughly 45mins. Check BS about every 15mins and act accordingly.If it drops give more glucose if it goes up don;t worry about it she is far safer having it go up than down.
I haven 't seen previous answers but judging by your comments there are some very ignorant and unfeeling people around.
I am a nurse as well and I caan totally appreciate your dilema . It is totally different dealing with a loved one your common sence goes out of the window and you panic....I have been there so many times!!!!
She will be fine Robin, just keep her still and don't worry about sending her sugar level up.
Hope this helps.
Love Mel.X
Question: Diabetics or healthcare workers, I need your help! Lantus users? I have some questions about Lantus (Glargine) insulin use with other blood glucose lowering agents. I read through the Lantus website, and through their FDA information that dosage can range from 2-100 IU per day. Starting with 10 IU once daily, then raising the dosage once per week according to a sliding scale by glucose level (+8 IU >180 mg/dL; +6 IU >140 mg/dL and so on...). In this case, the insulin was prescribed for use with Avandia, which we are stopping now bc the Avandia drug info says NOT to mix the two. So, back to the Metformin.
And just FYI so nobody freaks out... this IS being supervised by a physician with my help. I am an RN trying to help a friend learn about her diabetes and how to control it. Her glucose levels are consistenely above 300 right now! Yesterday she was taking 10 IU Lantus and 8 mg Avandia. Today she started taking 18 IU Lantus once daily and 1000 mg Metformin twice daily.
Now for the questions...
How much Lantus do you use?
How did you titrate it and how often?
What other diabetic meds are you taking and how much?
How were your glucose levels affected by the Lantus and meds?
Other than diet and exercise, is there any uselfull advice you would like to offer?
Have you ever used Byetta?
What happened?
Your help will be GREATLY appreciated!
THANK YOU THANK YOU THANK YOU TTC!!!!! That really helps! I have given Lantus before, but just in 10-20 IU doese. I was worried about going really high. But with your reassurance I will feel better!
Answer: A couple of years ago, I had glucose levels consistently in the 300s and sometimes 400s. Working with my dr. to find a way to lower while I refused to resort to insulin. The thought of being "insulin dependent" was psychologically unacceptable to me at the time. We tried metformin and actos in varying dosage amounts for nearly a year. My a1c was at 12 when I finally gave in. I started at 10 IU Lantus once daily and and continued with 1000mg metformin twice daily to not much change. We increased the Lantus by 2 IU weekly as long as my glucose levels (fasting) remained higher than 150. I got as high as 126 IU Lantus once daily, 1000 mg metformin twice daily and added back in the 30 mg Actos once daily. A1C began to come down gradually over the course of 9 months. We began reducing the Lantus by 2 IU weekly as long as fasting glucose level remains below 120. My most current labs were an A1c of 6.2, fasting glucose level at 60, eliminated the actos, lowered metformin to 500 mg twice daily, Lantus at 90 IU once daily and still decreasing on a regular basis weekly. What has helped me the most is a very consistent time of taking all the medications and having meals from day to day. Diet and exercise are key as we all know, but it was truly amazing how the timing was so important for me. If I alter the time of any of the medication and/or meals by just one hour...glucose level begins to elevate.
Never used Byetta.
Hope this helps with your friend. Good luck!
Question: ------> PLease Help Save My Cat!!! <------? Please Help Save My Cat!!!
Yesterday, the 16th, my 8-year-old cat, Dana, was diagnosed with Diabetes.
He was prescribed Glargine [Lantus Insulin] and needs 3 units of it every 12 hours.
Oh, and of course, it gets even better *sarcasm*. Turns out, the insulin costs $110 per month’s supply. We cannot afford this. If we don’t find out how to get cheaper insulin, we will have to put him to sleep.
If we get the insulin, though, he could go into remission. That means that his Diabetes will be cured. For the time being, at least. The vet says that if he goes into remission, the Diabetes won’t come back for about 4-5 years.
Please, please help me. He’s my baby, and I would be heart-broken if we had to put him to sleep.
All I need you to do is help me find cheaper insulin. I need a massive Google-Search team. Everyone, please, if you could look through all the webpages you can, and find out where they sell a lower-cost insulin, I would be eternally grateful.
Thank-you so much.
Thank-you, Simple, but I looked there and they don't have Glargine, the prescribed insulin.
Thank-you, though.
Answer: try.
this is the best advice i can offer you
ask the vet who prescribed the medication ~would it be possible to help him/her out for a period of time each week and get your cat 's insulin free or at least at an affordable price.
these are some sites that may help!!
http://marvistavet.com/html/glargine_ins…
do hope this helps
Insulin Glargine Related Products and News
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Family Practice News Digital Network
Insulin degludec, an ultralong-acting insulin now in clinical development, proved noninferior to insulin glargine in two parallel, phase III randomized trials sponsored by the manufacturer and reported in the April 21 issue of Lancet.
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PharmaLive.com (press release)
The two phase 3 studies included in total 1635 participants and investigated insulin degludec compared to insulin glargine in a basal-bolus regimen in people with type 1 and type 2 diabetes.1,2 Both studies were 'treat-to-target' studies, ...
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Diabetes Health (press release)
The phase 3 studies looked at 1635 people and compared the new insulin with a standard insulin glargine. It appeared effective for both type 1 and type 2 diabetes. For type 2s, it reduced the number of low blood sugar episodes to 11.1 per year, ...
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Family Practice News Digital Network
Following 84 weeks of treatment, patients with type 2 diabetes who received exenatide once weekly experienced better glycemic control with sustained overall weight loss and a lower risk of hypoglycemia, compared with those who received insulin glargine ...
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Zacks.com
Byetta should also benefit from the recent approval under which it can be used in combination with insulin glargine, with or without metformin and/or a TZD, for the treatment of type II diabetes in patients who are not achieving adequate glycemic ...
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MarketWatch (press release)
Biocon's key innovations include the world's first Pichia-based recombinant human Insulin, INSUGEN®, insulin analog Glargine, BASALOG® and India's first indigenously produced monoclonal antibody, BioMAb-EGFR®, for head & neck cancer.
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Amylin Pharmaceuticals Reports First Quarter 2012 Financial Results
MarketWatch (press release)
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Pulse
They have calculated that it could be lowered by at least £10000 per QALY, and potentially reduced to as little as £13000, in a move would have meant that drugs such as dabigatran and insulin glargine would never have been approved for use on the NHS.
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OnMedica
Two trials in the Lancet ? one in type 1 diabetes , one in type 2 ? investigate insulin degludec, which after injection forms multihexamer chains in subcutaneously, yielding a slower, steadier release. Both studies compared it with insulin glargine, ...
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Sanofi's strong 1st-qtr driven by Genzyme
The Pharma Letter
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